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Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate Specifications of Commercial Pure & BP Ph Eur EP JP USP IP Analytical Reagent FCC Food Grade Manufacturers & Exporters

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Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate CAS Number 37286-92-3

Calcium Polystyrene Sulfonate BP Ph Eur Grade:
Calcium Polystyrene Sulphonate
Action and use: Used in the treatment of hyperkalaemia.

DEFINITION
Calcium Polystyrene Sulfonate is a cation-exchange resin prepared in the calcium form containing not less than 6.5% w/w and not more than 9.5% w/w of calcium, calculated with reference to the dried substance. Each g exchanges not less than 1.3 mEq and not more than 2.0 mEq of potassium, calculated with reference to the dried substance.

CHARACTERISTICS
A cream to light brown, fine powder.
Practically insoluble in water and in ethanol (96%).

IDENTIFICATION
A. The infrared absorption spectrum is concordant with the reference spectrum of calcium polystyrene sulfonate.
B. Yields reaction C characteristic of calcium salts.

TESTS
Particle size: Not more than 1% w/w is retained on a 150-µm sieve. Use 20 g and sieve for 5 minutes.
Potassium: Not more than 0.1% of K when determined by atomic emission spectrophotometry, measuring at 766.5 nm and using a solution prepared in the following manner. To 1.1 g of the substance being examined add 5 mL of hydrochloric acid, heat to boiling, cool and add 10 mL of water. Filter, wash the filter and residue with water and dilute the filtrate and washings to 25 mL with water. Use potassium standard solution (100 ppm K), suitably diluted with water, to prepare the standard solutions.
Sodium: Not more than 0.1% of Na when determined by atomic emission spectrophotometry, measuring at 589.0 nm and using a solution prepared in the following manner. To 1.1 g of the substance being examined add 5 mL of hydrochloric acid, heat to boiling, cool and add 10 mL of water. Filter, wash the filter and residue with water and dilute the filtrate and washings to 25 mL with water. Use sodium solution (200 ppm Na), suitably diluted with water, to prepare the standard solutions.
Arsenic: 1 g complies with the limit test for arsenic, 1 ppm.
Styrene: Carry out the method for liquid chromatography. To pass the test --- (1 ppm).
Potassium exchange capacity: To 3 g of the substance being examined in a dry 250 mL glass-stoppered flask add 100 mL of a solution containing 0.7455% w/v of potassium chloride and 0.4401% w/v of potassium hydrogen carbonate in water (solution A), stopper and shake for 15 minutes. Filter and dilute 2 mL of the filtrate to 1000 mL with water. Determine the concentration of unbound potassium in this solution by atomic emission spectrophotometry, measuring at 766.5 nm and using solution A suitably diluted with water, to prepare the standard solutions. Calculate the potassium exchange capacity of the substance being examined in milliequivalents taking the concentration of potassium in solution A as 144 milliequivalents of K per liter.
Loss on drying: When dried at 70C at a pressure not exceeding 0.7 kPa for 16 hours, loses not more than 8.0% of its weight. Use 2 g.
Microbial contamination: Carry out a quantitative evaluation for Enterobacteria and certain other Gram-negative bacteria, Appendix XVI B1. 0.01 g of the substance being examined gives a negative result, Table I (most probable number of bacteria per gram fewer than 100).

SDS MSDS of Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate BP Ph Eur EP JP USP NF IP ACS Analytical Reagent FCC Food grade Manufacturers

Crystal Clear Products and the group companies are manufacturing chemicals since several decades. We have automatic vacuum operated titanium evaporators and SS316 equipments to produce top grade of chemical products. We have toll manufacturers and representatives in China, UAE, Europe, Canada & USA and agents & customers in all countries like USA, Canada, Europe, UAE, South Africa, Tanzania, Kenya, Egypt, Nigeria, Uganda, Turkey, Mexico, Brazil, Chile, Argentina, Bangkok Thailand, Kaula Lumpur Malaysia, Dubai UAE etc. & sales representative in Chicago, Houston New York & Los Angeles, USA. Associated units are FDA-GMP certified, Halal and/or Kosher certified, REACH registered, ISO-9001, ISO-22000 HACCP certified, Crisil Rated.

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Crystal Clear Products
Plot No-C1-1031-9, GIDC Estate, Panoli, Ankleshwar, Gujarat - 393002. India
Telephone Mobile: 91-7506449333; e-mail: info@crystalclearproducts.org

e-mail: info@crystalclearproducts.org

Manufacturers, Suppliers of IP BP Ph Eur EP JP USP NF FCC Food, ACS Reagent Grades of Chemicals like Calcium Polystyrene Sulfonate or Calcium Polystyrene Sulphonate